IVF with PGT

IVF, ICSI, and IVF with PGT: Different Tools for Different Questions

These options are not simply older-to-newer generations. They address different questions: fertilization method, male-factor infertility, and embryo genetic testing. Fertilo-P focuses on supporting egg maturation and potentially reducing stimulation burden within the broader IVF with PGT pathway.

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How IVF, ICSI, and IVF with PGT Differ

The real decision is whether the main issue is fertilization, fertilization assistance, or embryo genetic testing.

IVF

Conventional Fertilization

Where fertilization happens

Eggs and prepared sperm are placed together in the lab, allowing fertilization to happen without direct sperm injection. It may fit tubal, ovulatory, unexplained, or selected cases with acceptable semen quality.

ICSI

Intracytoplasmic Sperm Injection

How fertilization is assisted

An embryologist injects one sperm directly into an egg. It is often used for male-factor infertility, previous failed fertilization, surgically retrieved sperm, limited frozen sperm quality, or some embryo testing cycles.

IVF with PGT

Preimplantation Genetic Testing

What can be checked before transfer

After embryo culture, a biopsy can be tested for chromosomal aneuploidy, single-gene disorders, or structural rearrangement risks, helping guide embryo transfer choices.

Dimension IVF ICSI IVF with PGT

Core action Eggs and sperm co-incubate One sperm is injected Embryos are genetically tested

Main question Standard fertilization and culture Sperm factors or failed fertilization Genetic risk before transfer

Often considered for Tubal, ovulatory, unexplained factors Male factor, surgical sperm retrieval Advanced age, repeated loss/failure, genetic risks

Important limit Does not solve all fertilization issues Assists fertilization, not egg quality Screens embryos, not a pregnancy guarantee

Fertilo-P

Fertilo-P Advantage: Supporting the Egg Maturation Environment

PGT happens at the embryo stage, but embryo development starts with egg maturity and the ovarian microenvironment. Fertilo-P uses iPSC-derived ovarian support cells to help immature eggs mature in a lab environment designed to mimic ovarian support, then connects into fertilization, embryo culture, and PGT. View Fertilo-P Core Technology

Gentler Stimulation Concept

Fertilo-P centers on ex-vivo maturation support, aiming to reduce dependence on long, high-dose stimulation for selected patients.

Ovarian Support Environment

iPSC-derived ovarian support cells provide nutrients, signaling, and feedback designed to mimic a more supportive follicular environment.

Connects to Fertilization and Culture

Mature eggs can proceed to fertilization, blastocyst culture, PGT biopsy, and transfer planning within the IVF with PGT workflow.

Clearer Planning

For low ovarian reserve, limited egg yield, or prior poor embryo outcomes, it can become an important discussion point with doctors.

How Fertilo-P Connects With IVF with PGT

Fertilo-P does not replace PGT. It supports the egg retrieval and maturation side, while PGT remains the embryo genetic testing and transfer-selection step.

Record Review

AMH, AFC, semen, previous cycles, genetic risks

Choose Fertilization Path

IVF, ICSI, or IVF with PGT planning

Assess Fertilo-P

Whether egg maturation support may fit

PGT Testing

Embryo testing and report review

Transfer & Follow-up

Transfer window and pregnancy confirmation

Important Note

This page is for education and consultation preparation, not medical advice. The choice of IVF, ICSI, IVF with PGT, or Fertilo-P suitability should be assessed by doctors using age, AMH, antral follicle count, semen quality, previous embryo results, genetic risks, and local regulations.